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Enterobacteria phage P22
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Enterobacteria phage P22 : ウィキペディア英語版
Enterobacteria phage P22

The Enterobacteria phage P22 is a bacteriophage related to bacteriophage λ that infects ''Salmonella typhimurium''. Like many phage viruses, it has been used in molecular biology to induce mutations in cultured bacteria and to introduce foreign genetic material. Upon its discovery, P22 has been used in generalized transduction and is an important tool for ''Salmonella'' genetics.〔
==Morphology, classification and relatives==
P22 shares many similarities in genetic structure and regulation with bacteriophage λ.〔 It is a temperate double stranded DNA phage as well as a lambdoid phage since it carries control of gene expression regions and early operons similar to those of bacteriophage λ.〔 However, the genes which encode proteins that build the virion are different from those of bacteriophage λ.〔 P22 has a 60 nm diameter icosahedral (T=7) virion head and a short tail.〔 This virion morphology puts P22 in the formal ''Podoviridae'' group.〔 Related viruses with similar genomic transcription patterns and life cycles include bacteriophage λ and all the other lambdoid phages. Other relatives with similar short-tailed morphology and DNA homology in the protein genes of the virion include bacteriophages λ and Ε34.〔 Many ''Podoviridae'', for example phages T7 and Φ29, share few DNA similarities with P22, even though their virion morphologies are similar.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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